USC vs. Northwestern Predictions - Jan. 21

The Northwestern Wildcats (8-10, 0-7 Big Ten) will visit the USC Trojans (14-4, 3-4 Big Ten) after losing four straight road games.

USC is a healthy 6.5-point favorite against Northwestern when the Trojans play the Wildcats on Wednesday. The over/under for the game is 149.5.

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USC vs. Northwestern Odds and Game Info

  • Game day: Wednesday, January 21, 2026
  • Game time: 11 p.m. ET
  • TV channel: Big Ten Network
  • Location: Los Angeles, California
  • Arena: Galen Center

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USC vs. Northwestern Odds and Prediction

  • Spread favorite: USC (-6.5)
  • Moneyline: USC (-302), Northwestern (+242)
  • Total: 149.5 points

Pick ATS:Northwestern (+6.5)

  • Pick OU: Over (149.5)
  • Prediction: USC 79, Northwestern 75

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USC vs. Northwestern Comparison

USC Rank USC Stat Northwestern Stat Northwestern Rank
64th 83.4 Points Scored 77.3 171st
237th 75.8 Points Allowed 71.9 128th
62nd 16.5 Assists 17.8 24th
288th 12.5 Turnovers 8.2 1st
73rd 47.4% Field Goal % 47.0% 94th
71st 41.7% Field Goal % Allowed 42.5% 108th

USC Key Players

  • Chad Baker-Mazara leads the Trojans in points and assists per game, scoring 18.9 points and distributing 3.2 assists.
  • Jacob Cofie is USC's best rebounder, hauling in an average of 6.8 boards in each contest while scoring 10.0 points per game.
  • Baker-Mazara makes more threes per game than any other member of the Trojans, knocking down shots from beyond the arc at a clip of 2.1 per contest.
  • Cofie is USC's leader in steals and blocks, racking up 1.1 steals and 1.7 blocks per game.

Northwestern Key Players

  • The Wildcats' leader in scoring and rebounding is Nick Martinelli with 23.7 points and 6.8 rebounds per game.
  • Northwestern's assist leader is Jayden Reid with 5.4 per game. Reid also scores 11.6 points per game and tacks on 1.9 rebounds per game.
  • Martinelli is dependable from three-point range and leads the Wildcats with 1.4 made threes per game.
  • Reid (0.9 steals per game) is the steal leader for Northwestern while Arrinten Page (1.2 blocks per game) is the block leader.

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